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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b385149be74a4b043f6b4f927ba786862660ca8c1dd562cdef34fa1d506212f1' 
  AND token = 'kmcb231cnPjZ/bFs8ERwdf4eSpZum50WjgSgGcreGAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}