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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e468ea482accff54c687871f9defd305cb775a681ba59f38f8c0a62a5d00d413' 
  AND token = '3lN/trvzyAdgbw41ZVCukRsKnA10lvrGvDrKJn56IUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}