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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd59a8cfa9bdbc8f85e46d65b56d5d28542d12a8f005ba6427c849af5f1daa116' 
  AND token = 'cHow+ney7Y0dVIEypa/moO7ZW5Ge8joKQoiTHUWLdZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}