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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e8dc196368537d61cd490d6f4d1073b2181664784cef1a531c83b4d138e1a7' 
  AND token = 'VPpNVCcMNPCL60JA1dCS3BICzHN/DQ03mkT7dKnXuiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}