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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00e3d709607887c863324e3b0bf9a9da3422cc304d3063bed8027cf731b33713' 
  AND token = 'zN8fEdWjNEDyetftqn+WWwm66r1OZO7xUN3CA+TvUwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}