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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2144feb287568fb7c1d613826c758f7c8ec15a9c7e738550fddfcccc88e61fd3' 
  AND token = 'y1XXhSbT+ULr2hi26u1DQ1zFiNdbDkRdoaprFKMYan8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}