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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22cdc1c50f8ff6532d8bad93fe1e7b8151b10c87e8d3a8281895431122d2fdc' 
  AND token = 'xMNWR3+SdmOsz/L2JJIm8UAiX3U++cu5shC34NodsGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}