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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17596a1aede3aa325c47da39c62602f172c6dbe3b868e3be4577d191599fe673' 
  AND token = '8h5NUBdKT44E919tLggmjNsoimsBhyi8wtzs8hwjrMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}