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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4257dc5a6723648f483cdaf04852e78bbf8ea7eb2d0eab3a924a8b56361610b7' 
  AND token = '0q3mjbc/LMe//C2crmfv2QkvS3AGxRxd+KvFGWBTxVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}