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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e29356b1cf004e7a0956a6b3159897abc43d3adc04bff3ae74a6c0c04e0f2de' 
  AND token = 'hJs43in8WucJ+u55gZhpzJdCAo4hK/np2nqyfGs2lDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}