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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93d0b1765b0852a8833606e51b881a1edfa7c491c27490547a65671a847e98af' 
  AND token = 'ZX/xz1gyqOKJTelJR1UaK4hX4uXf8cNjP2QTQiKRxao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}