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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac05bc79a314ef2d11f63876f4c1d6936c5ad035e9c05f526f1b76be60a2c357' 
  AND token = 'JwIzQbhvASqzRu6BpbPtx9UiADOc9oRU1w8EorYyLiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}