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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '899a2c53726e4808b82448e019d3246de9aea7e7b3d598a468ea9363f7742d26' 
  AND token = 'U9JCCXcZF+rP1oHkQCoUxUr+Zn973FH0vmn8F2uW4nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}