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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21cde3839cd563d5477683d6fa35d81b02231bebd61f62d4bd6c779cec330077' 
  AND token = 'MQ1jEvryZQedGLXJhYRIiuQQjK2/fVAo8+L6MDUcfmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}