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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c39d0aa9e84e849b10cc4fffb4ef388a3e5edef3a9a0016e4b704e106edba06b' 
  AND token = 'am+2zh66r1rEYzPTkpH2TvuXfHwHiMNiOe3viG66TtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}