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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e420c39e58b802efe43ba7788dfa0ea1dc8b210c78393e4f69d598f11127f95b' 
  AND token = 'bn0eBIgOGIFeQL5kY11uiehl7b+HthTMHcKFzJnrMZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}