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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8d6692dfa48fa58f858ae0e531a878674f00ce19a90962f23926f57d17eed12' 
  AND token = 'IIr+pcigDlTOvnn1rhA/g5KDgVG59I6AW9gY5HLRRXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}