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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20102a7b9d7a40f3d5d7c9d23eb554d397dd9bd3cf3780797518daf308ad2074' 
  AND token = 'Ls8wzlsnjk4ilvRwVD2vf/cyNz67bFw4jBGELzW9Ssg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}