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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab2b0340b5aafe35705e6e93139c4cf311fea9f3bb19a0dd0d1998ce69e8f399' 
  AND token = 'O1E/u/gpi6dN8N1mS/DTC3TX9lVi4dMXEMxHAtLKI4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}