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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f5ed732812ba721054439880bc8401d77288b1f02e4cb2a308c5788769a8273' 
  AND token = '/DeQmNdrdgnvwqvwbdcI7nk0KUqkeQzZ0LtE9xubr2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}