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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3781094a9b71332b998fb1a4c40a9da134eb5103ef356baedcef729b6b0df3d1' 
  AND token = '+9dhxNjVol/LFhU08C3FvKl/DO5fY3+HFTS2Wf1C1fA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}