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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ed0ee477105ed37f770a1ccc78f53445fd8914ab0717a8f2d7a72bbac262dfb' 
  AND token = 'jIiTdEcLC9jIFhXYCN3oMVVe3K5FdcFKTDnYOMvTVNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}