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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '299d8b6a8f8c28d1dce2222991a343099f3a321b6f67852587ec74aab380e613' 
  AND token = '1fNPdCypu0BBmJBUEtOXUQTe8HN3F1GKLl9W5E1UEWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}