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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fde5e665c2a860737def3cdf81f3065f8dca7c38a506d07ab97a046fed5adcea' 
  AND token = 'rQ/CRYnBdDOXLmCKlf5IowRAQHZmlY8UADQSOjY963w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}