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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f176b546aeb5ef83b001a31eb249976d48089e8d3818caf782eddad1b70a4dc' 
  AND token = 'N/fXrdpd+2PCv3DYn//TNF86esANT52fLL4y0ZPMn6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}