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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5307275902cc380b4e6323b089e7a7c0b3762a20075245d60493fa7a51d01c3' 
  AND token = '74AAIX2DQfXTMU/9Xq5RSnrrkVNpsa3MBVu+8lBKdTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}