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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105548a0c6ebf5d4647c5e76a177ce5459bdbe4d376543e14e92c63944163505' 
  AND token = 'Jcddm0I8+E41RAXHzBT2EidsZZvOEhPvtI9GfUT9vlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}