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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49bf3aaf19201e70e17e1c4dcdcc2a7d3b2ddc3a7a726df1e67594724aaf7a1' 
  AND token = 'Y6JKLnDaR3310kk/L2I+gepx/YeB4n2FkcyIe6Vhr/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}