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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b7f59ac5428bea31e389b53be13fa3ccf33096e62183965b8efea42e30d3d2' 
  AND token = 'o+NKeukXVIJWvYeQ94Yt8p5e9oJWS+RmhcxqLbEcDCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}