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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9a5f8c89cfef49769d100894cc251ca5ec72643ca6a7b24ef3b3ed63e1cb844' 
  AND token = 'V0zLtLymobpDwE9PSqWd2OS/bWhM72qjSTHzHQpsWB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}