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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddf0543b308124791bd9f931276f5eb3d581d1d1f94c913811c4eaec217db846' 
  AND token = 'yGrtNlTY23RADXZq6CzoQ2KB4hOfMAcRwQVDN60V8DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}