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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cd24f1b041f810d02481ff43e7d5f8649a2a96568c87c81af7b2dcbd57ac213' 
  AND token = '43wlitYE88zJsACl6Sgn9NhF1fkox651Ik8CsxxDe1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}