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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def7521a0c126cd5aa73fb1a9c3ae39200b411c6ea0f42e919c914e203f7d3c9' 
  AND token = 'I5WuemTzUJ80jCWmmFbHw32rTno8GNUUcpapBaG6+0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}