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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e022e773f6d84b6ca41537d18a8c8ce5dea3dddb7ffb7aa13c667db76b29d08' 
  AND token = 'ISqdOir96fuuKPtCb5F9ym84dsA/mh551+ZPax7mwrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}