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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a59e26081d18130818d319d925a266ec9782f9b1f230c126fcc359ff054fe6e' 
  AND token = '3yxOy3jCdJOybULUWqpIDDHTkx2yyDv9djZkVUrIYZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}