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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c73a3655c6d868aa49e46fe138bfe24a31a1ba3948f7ec2e00d86a8192688cdb' 
  AND token = 'DPMiv3kGuX/mU28N7iuZDU9nk7f2RFxFd2WXeGfif04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}