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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e4067c3d62fd0522b9fd61591f8c3502d4741c53769df2d08c29f3e4e2eee86' 
  AND token = 'C+7N8Wp5cHBT4H3SwfKmp4OiKbHkB05wI36sQ/G9VJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}