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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34ecd760de3a041a31e7688e1fb043beea3792ea4eaf9d2b5edc060ac98c6688' 
  AND token = 'LoakeDsL4H5Owm26UuvA3KW6zVA4pgxAMOdfL1Bw1FM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}