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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c63c503424bdf5a0a468e038b4eb9edd5f288df99cd9880b973268d3854bdb9a' 
  AND token = '14/eZW+Tm373avyh2+C1MFyJj7WJPoQKUS4GhFllt9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}