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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a44e78ada84553ab9af817b66e8e761ec4661af09d5bd55a5f4d3c4d8ee7fe' 
  AND token = 'r5WbCqYf2INT+ZGCSTpxNZRvAMd4HIwKa5nINjItS4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}