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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9164e292aac0a250f2321a3ff017e0cf434b6e0f47bfecd2e7962eca3c384cc5' 
  AND token = 'a6d5oQDN5ajy/ErCAjIPwOIxF7BRsfbWDiQ216eDgZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}