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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55c405a077ccf7bf9365c4d556e9c3bf99c1882463a992ba5f9e1233fd8afb64' 
  AND token = 'Ej0Mp8Zc/2mr9YWrjCKRAtjEez7KaKG2IzbI43aaVaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}