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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0b45d90890cdaa2c7edfa9da9bbd638c4c9d5fea36bf3be03757dc6b2fff4d2' 
  AND token = 'XZSfjQAPFf9DPw/iJEHAgKPCTo32EtZqiyLzPDFHOwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}