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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72de19e69d45c3d0a8f45385079e9eac9d4fd7ed83ca695455592e4f5c8996ac' 
  AND token = 'pgHJPGIhUAVHLM+ngBVt51Qv+i5UMWIaw1Y3UQ+H8e0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}