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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26267ad771748d364be4a0052710e16c9a072d2f3dff6230e2e7e1beb908f0d8' 
  AND token = 'sFTReWLhhSS502oV6PUq0ESIqhnO/qhL3k7M4erPcGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}