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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afde569c5d50ceadde5ab93a5b90678dc4cb2c33e4428d6cffae6e74085f8258' 
  AND token = 'qghA0GJM31VFS8/Fmks+wbPOWi0MxUok+KfanEhwNW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}