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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '507b2b2fe9a060c4a7cfff43c009326c34efb112808c5cb42b773f141883d343' 
  AND token = 'ph6wMtq/ClPkaZrk7FN2veXefSwhqmLGSFiVqN3A5JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}