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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c46dc41d15b4034b25796f406f7e9a64d0bed6b7ce847e27771416aca871f8a' 
  AND token = 'zvelbsQ/0eu1fS7jvmhYhgG6RAP/oAD08Ybh4+eOxWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}