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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a8270a53ca088053a9e5604dc3255e8c626ca8011121075806b6e3a364e4e62' 
  AND token = 'Q26JyhQz6sIGMUxkUjWfnxLu55G/hZrWqCKjHkq9E4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}