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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '123eaf493e6458aed64fef4f9f92c8652fc01a398501176e13630cfd4695f614' 
  AND token = 'jKSbAbHiDmUiK0SLqiFckNsiUHslwBMtVkAT06tgIus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}